Polypyrimidine tract-binding protein ptb
WebMar 4, 2004 · The polypyrimidine tract binding protein (PTB) is an important regulator of alternative splicing that also affects mRNA localization, stabilization, polyadenylation, and translation. NMR structural analysis of the N-terminal half of PTB (residues 55-301) ... Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆
Polypyrimidine tract-binding protein ptb
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WebPTB (polypyrimidine-tract-binding protein) is a ubiquitous RNA-binding protein. It was originally identified as a protein with a role in splicing but it is now known to function in a … WebMay 26, 1995 · In higher eukaryotes, the polypyrimidine-tract (Py-tract) adjacent to the 3′ splice site is recognized by several proteins, including the essential splicing factor U2AF 65, the splicing regulator Sex-lethal (Sxl), and polypyrimidine tract-binding protein (PTB), whose function is unknown.Iterative in vitro genetic selection was used to show that these …
WebPolypyrimidine-tract-binding protein (PTB) is involved in pre-mRNA splicing and internal-ribosomal-entry-site-dependent translation. The biochemical … WebApr 14, 1998 · Polypyrimidine tract-binding protein (PTB), also known as hnRNP I, is a member of the hnRNP family [2-4]. PTB has been proposed as a splicing factor, since PTB was identified as a protein binding to the polypyrimidine tracts (Py-tracts) typically found near the 3′ end of introns [3, 4].
WebPolypyrimidine tract-binding protein homolog 1. Gene. PTB. Status. UniProtKB reviewed (Swiss-Prot) Organism. Arabidopsis thaliana (Mouse-ear cress) Amino acids. 399. ... PTB. ORF names. T4P13.16. Ordered locus names. At3g01150. Organism names. Organism. Arabidopsis thaliana (Mouse-ear cress) Taxonomic identifier. WebMar 26, 2024 · Polypyrimidine tract-binding protein (PTB) is necessary but not sufficient for regulation of tropomyosin splicing. alternative splicing of brain-specific PTB has an …
WebJan 1, 2006 · The polypyrimidine tract binding (PTB) protein is a potent regulator of alternative mRNA splicing. It also participates in other essential cellular functions, including translation initiation and ...
WebPolypyrimidine tract-binding protein (PTB), as a member of the heterogeneous nuclear ribonucleoprotein family, functions by rapidly shuttling between the nucleus and the … china wall restaurant concord caWebSep 23, 2005 · The polypyrimidine tract binding protein (PTB) is a 58-kilodalton RNA binding protein involved in multiple aspects of messenger RNA metabolism, including the repression of alternative exons. We have determined the solution structures of the four RNA binding domains (RBDs) of PTB, each bound to a CUCUCU oligonucleotide. granby profitez guichetWebApr 10, 2024 · The structural integrity of the PNC is dependent upon its RNA and protein components and is mediated by the RNA-binding ribonucleoprotein, polypyrimidine tract … granby property cardschina walls oahu addressWebFeb 22, 2012 · Various IRES-binding factors, such as eIF4G, polyA-binding protein (PABP), polypyrimidine tract-binding protein (PTB) and poly(rC)-binding protein 2 (PCBP 2), are targets of picornavirus proteases supporting a link between picornavirus gene expression and inactivation of nuclear and cytoplasmic RNA-binding proteins. ... china wall slot gameWebFeb 22, 2004 · Tillmar, L. & Welsh, N. Hypoxia may increase rat insulin mRNA levels by promoting binding of the polypyrimidine tract-binding protein (PTB) to the pyrimidine-rich insulin mRNA 3′-untranslated ... granby property recordsWebDec 6, 2016 · For example, depletion of the polypyrimidine tract binding protein PTBP1 (PTB or hnRNP I) induces PTBP2 (brPTB or nPTB) expression in most cells (Boutz et al., 2007, Makeyev et al., 2007, Spellman et al., 2007). Some targets require depletion of both proteins to alter splicing (Han et al., 2014, Linares et al., 2015). china walls in homes