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Glycerol turnover

Web2. From a study of the release of [14 C]glycerol from pre-labelled brown fat, it is concluded that the tissue contains a pool of glycerides with a higher rate of turnover than those in the main lipid store. 3. This pool contains newly synthesized glycerides, has a half-life of 25–30min and supplies about 25% of the glycerol liberated by brown ... WebMar 10, 2024 · Genes involved in protein turnover, including those encoding ribosomal proteins, translation elongation factors, and genes involved in building the proteasome also showed an enhanced transcription in CGHH compared to CG. ... To identify genes and metabolic pathways active during glycerol turnover in R. toruloides CBS14, cells were …

Lipidome-wide 13C flux analysis: a novel tool to estimate the turnover …

WebFeb 12, 2015 · In order to examine the respective roles of hepatic acetyl CoA and glycerol turnover in the regulation of HGP by insulin, we infused awake rats with insulin to mimic physiologic postprandial insulin concentrations during a hyperinsulinemic-euglycemic clamp and found that plasma non-esterified fatty acid (NEFA) and glycerol concentrations were … WebPalmitate and glycerol turnover were determined using the steady-state calculation (infusion rate divided by specific activity or enrichment) in view of the relatively short time for glycerol enrichment (4) and FFA spe- cific activity (25) to reach a steady state. The deuterated glyc- erol infusion rate was subtracted from the total glycerol ... hrdf act malaysia https://bear4homes.com

Metformin inhibits gluconeogenesis via a redox-dependent

WebJul 23, 2024 · For alanine and glycerol turnover, rats were primed for five minutes at 3 × the continuous rates and then continuously infused for 120 min with tracer as follows: 10 μmol kg –1 min –1 [3-13 ... WebIn both postabsorptive and starved rats, glycerol turnover rate (Rt) and the percent … WebAug 21, 2024 · Glycerol is synthesized and secreted by adipocytes to dispose of excess glucose, via glycerogenesis and increased acyl-glycerol turnover Introduction. Intact white adipose tissue (WAT) (and isolated … hrdf blueprint

The turnover of glycerol and acyl moieties of cardiolipin

Category:Mechanisms by Which Liver-Specific PEPCK Knockout Mice …

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Glycerol turnover

Enhanced glycerol assimilation and lipid production in …

WebThe global glycerol market is expected to exhibit a CAGR of 7.2% during 2024-2027. … WebIncreased glycerol turnover in the setting of lower plasma and hepatic triglycerides indicates that glycerol is fueling gluconeogenesis rather than being used to esterify fatty acids. Taken together, elimination of PEPCK-M from gluconeogenic tissues from otherwise healthy adult rats significantly impacts glucose homeostasis.

Glycerol turnover

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WebFeb 1, 1994 · Although the ratio of non-esterified fatty acid to glycerol release by adipose tissue increased in all subjects from a mean value of 2.7 in the basal period to 3.7 at 50 and 60 min of the noradrenaline infusion, respectively, at no time point did the ratio differ significantly from 3.0. 1. The effect of infusion of noradrenaline (0.42 mumol min-1 kg-1) … WebGlyceroneogenesis,i.e. the synthesis of the glycerol moiety of triacylglycerol from …

WebThe oxidation and turnover of plasma glycerol has been studied in lean and obese, fed and starving man by means of a long-term infusion of glycerol-14 C, and the participation of glycerol in gluconeogenesis has been determined.Under none of the experimental conditions did glycerol contribute more than 10% of the total respiratory CO 2.Glycerol … WebFinally, continuation of GH induced moderate elevations in plasma glucose levels without significant changes in total glucose turnover or oxidation. In summary, continued GH substitution during fasting conserves nitrogen, which involves stimulation or maintenance of protein synthesis.

WebApr 28, 2015 · To measure hepatic gluconeogenesis, whole-body palmitate and glycerol turnover, we performed a 120 min infusion of [3-3 H] glucose (0.05 μCi/min), [1,1,2,2,3-d 5] glycerol (1.5 μmol kg −1 min ... WebJan 1, 2024 · With these isotopomers, we calculated turnover rate constants, half-life times, and fluxes of the glycerol backbone of multiple lipid species. To perform these calculations, we estimated the fraction of labeled molecules in glycerol-3-phosphate, the lipid precursor, by mass isotopomer distribution analysis of the spectra of phosphatidylglycerol.

WebApr 1, 2014 · The turnover of glycerol groups was monitored by specific isotopologues that carried 13 C primarily in the glycerol carbons, whereas the turnover of acyl groups was monitored by molecular species that carried myristoyl or 2 H 2-oleoyl groups. We found that the turnover of CL, but not of mitochondrial PC and PE, was substantially slower than …

WebApr 1, 1992 · To study the initial period of fat deposition in human obesity, we measured glycerol turnover in 12 children of 135–253% ideal body weight, who had continuously gained weight since the onset of obesity 2–9 yr previously. Hyperinsulinemia developed in these children depending on obesity duration (r = 0.74, P < 0.01). hrdf borang 1aWebThe oxidation and turnover of plasma glycerol has been studied in lean and obese, fed … hrdf borang 4aWebJan 1, 2024 · Prolonged fasting increases glycerol turnover and decreases lactate and glucose turnover. A, Experimental scheme of 13 C tracer infusions. B-D, 13 C average carbon enrichment of serum metabolites at steady state infused with 13 C 6 glucose, 13 C 3 lactate, or 13 C 3 glycerol tracers. E-G, Turnover rate (F circ) of circulating glucose, … hrdf borang 1 onlineWebNov 1, 2014 · After 7 days of CL treatment, both DNL and glycerol turnover were elevated in all fat pads, with the highest turnover in BAT (Fig. 2A vs. ). However, the increase in glycerol turnover was comparable at days 1 and 7 of CL treatment. These data indicate that CL induces a futile substrate cycle of lipolysis and reesterification without a net ... hrdf certificateWebNov 2, 2024 · Main effect plots for results from a 3 2 full factorial experimental design with acetic acid to glycerol molar ratio of 4.4. (i) Turnover frequencies for glycerol with the reciprocal of moles of active sites (μ *−1). Values of moles of active sites (μ *) of 0.62, 2.04 and 3.45 mmol. (ii) Variation of the turnover of the glycerol consumption ... hrdf capaiWebMay 16, 2003 · Basal rates of whole-body glycerol turnover and insulin suppression of glycerol turnover during the clamp were similar in the elderly and control participants. Consistent with this finding, the interstitial glycerol concentrations, assessed by microdialysis, decreased by a similar degree during the clamp in both groups. hrdf allowanceWebOct 1, 2007 · We combined tracer and arteriovenous (a-v) balance techniques to evaluate the effects of exercise and endurance training on leg triacylglyceride turnover as assessed by glycerol exchange. Measurements on an exercising leg were taken to be a surrogate for working skeletal muscle. Eight men completed 9 wk of endurance training [5 days/wk, 1 … hrdf approved training provider list